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GHK-Cu

Copper Peptide

Supports collagen production, skin repair, and hair growth

Repair & RecoveryPeptideRoute · SubQ / topicalReviewed Apr 2026
01 — OVERVIEW
SYSTEMSHow GHK-Cu affects you

Rebuilds skin, hair, and connective tissue.

A copper-carrier tripeptide that signals fibroblasts to lay down collagen, elastin, and glycosaminoglycans — the core scaffolding of youthful skin.

Collagen
+70%
in vitro fibroblasts
Onset
4–8 wk
  • Best-documented effect: skin firmness, wound healing, and hair density.
  • Activates stem cells in hair follicles when applied topically.
  • Reduces visible lines and thickens dermis in clinical dermatology studies.

GHK-Cu is a small copper-binding peptide that your body produces naturally — but levels decline sharply with age. It signals skin cells to make more collagen and elastin (the proteins that keep skin firm), accelerates wound healing, reduces inflammation, and may increase hair follicle size.

02 — PHARMACOKINETICS

How long it stays, how it leaves.

Half-life
2 h
Default concentration
5000 mcg
Common vial sizes
5000 / 10000 mcg

Fixed dosing — not weight-adjusted. The calculator handles reconstitution math for common vial sizes so you inject the right volume every time.

03 — DOSING PROTOCOL

Three tiers, three goals.

beginner4 weeks cycle
Dose
200500 mcg
Frequency
Once daily
Cycle
4 weeks
intermediate8 weeks cycle
Dose
5001000 mcg
Frequency
Once daily
Cycle
8 weeks
advanced8-12 weeks cycle
Dose
10002000 mcg
Frequency
Once daily
Cycle
8-12 weeks
04 — SIDE EFFECTS

What people actually report.

  • Skin flushing
  • Mild irritation at injection spot
  • Temporary redness with cream use
05 — WARNINGS

Before you start.

  • Your body already makes this naturally, so it's well-tolerated
  • Cream/topical is the most common and safest way to use it
  • Talk to a doctor before injecting
06 — STACKING & INTERACTIONS

Combinations worth knowing.

Connective Tissue Repair

BPC-157 builds new blood supply while GHK-Cu rebuilds the collagen framework. Like fixing both the pipes and the walls.

07 — CITATIONS & Q&A

Research behind the claims.

Pickart L, Margolina A. · International Journal of Molecular Sciences · 2018
GHK-Cu upregulates over 4,000 genes involved in tissue repair, anti-inflammatory response, and antioxidant defense.
Pickart L, Vasquez-Soltero JM, Margolina A. · BioMed Research International · 2015
GHK-Cu stimulates collagen and glycosaminoglycan synthesis in fibroblasts and activates stem cells in hair follicles.

Ask anything, get cited answers.