Methodology & Sources

Our editorial principle

PepTalk is an educational tool, not a medical service. Our goal is to translate the primary literature on peptides and nootropics into plain English — without hype, without marketing spin, and without recommending anything specific to any individual. Every compound page is written to be read by someone with no medical background.

Where our data comes from

• ·Peer-reviewed literature — PubMed, clinical trial registries (ClinicalTrials.gov), and published reviews are the primary source for mechanism of action, side effects, and pharmacokinetic data (half-life, bioavailability).
• ·Regulatory filings — FDA labels, EMA documents, and drug monographs are used for compounds with approved clinical indications (e.g. semaglutide, tesamorelin).
• ·Dosing protocols — Ranges reflect commonly reported doses from published research, clinical guidelines, and long-standing practice. Ranges are not prescriptions.
• ·Safety & interactions — Drawn from clinical trial data, case reports, and pharmacology references. We err on the side of listing more cautions rather than fewer.

How the calculator works

All dose math is performed locally in your browser. No dose data is ever sent to our servers. The core formula is straightforward:

Syringe unit math assumes a standard U-100 insulin syringe (100 units = 1 mL). If your calculated volume exceeds your selected syringe, the calculator warns you and suggests a larger size.

How we keep pages current

Each compound page carries a “Last reviewed” date. We review pages whenever new clinical trial results are published or regulatory status changes — at minimum, every 6 months. If you spot something that looks out of date or inaccurate, please email us and we'll investigate.

What PepTalk is not

• ·PepTalk is not a replacement for medical advice, diagnosis, or treatment.
• ·We do not sell, supply, or endorse any specific vendor or product.
• ·We do not recommend specific doses for any individual. Ranges are educational references.
• ·Most compounds on PepTalk are not FDA-approved. Research chemicals are regulated differently than medications — know what you're reading about before using it.