Phosphatidylserine
Strengthens your brain cells from the inside out — sharper memory as you age
Calms stress hormones in the brain.
A phospholipid found at high concentrations in neuronal membranes. Supplementation blunts the cortisol response to exercise and cognitive stress.
- Studied in age-related memory decline and ADHD in children.
- Most convincing effect is on reducing stress-driven cortisol spikes.
- Well-tolerated and low side-effect profile long-term.
Your brain cells are wrapped in a protective wall called a membrane. Phosphatidylserine (PS for short) is one of the main building blocks of that wall. When your brain cell walls are strong and healthy, signals travel between them faster and more accurately — like having a crystal-clear phone connection instead of a staticky one. PS also helps lower stress hormones after exercise and is one of the best-studied supplements for keeping your memory sharp as you get older.
How long it stays, how it leaves.
Fixed dosing — not weight-adjusted. The calculator handles reconstitution math for common vial sizes so you inject the right volume every time.
Three tiers, three goals.
300mg is the dose used in most studies
What people actually report.
- Mild sleep issues at high doses
- Rare stomach upset
- Overall very well tolerated
Before you start.
- The FDA actually allows health claims about PS and brain function — that's rare
- One of the most researched brain supplements out there
- If you're allergic to soy, look for sunflower-derived PS instead
- Also helps lower the stress hormone cortisol — nice bonus
Combinations worth knowing.
Memory Stack
PS strengthens your brain's hardware (cell walls) while Bacopa upgrades the software (connections between cells). The ultimate memory combo.