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Pinealon

The Pineal Peptide

Resets your body clock for better sleep and mental clarity

NeuroactivePeptideRoute · oral / SubQReviewed Apr 2026
01 — OVERVIEW
SYSTEMSHow Pinealon affects you

Supports the aging brain at the DNA level.

A short peptide developed in Russia. Appears to regulate gene expression in neurons and reduce age-related cellular damage, particularly in the pineal and hippocampus.

  • Russian longevity research suggests improved cognitive markers in the elderly.
  • Very limited peer-reviewed data outside of the original research groups.
  • Considered experimental — mechanism and claims aren't well-validated in the West.

Pinealon works on the pineal gland — the tiny part of your brain that controls your sleep-wake cycle. Think of it like resetting a broken alarm clock. It helps your body produce melatonin and serotonin at the right times, so you fall asleep easier and wake up sharper. Great for jet lag, shift workers, or anyone whose sleep schedule is messed up.

02 — PHARMACOKINETICS

How long it stays, how it leaves.

Half-life
2 h
Default concentration
5000 mcg
Common vial sizes
5000 mcg

Fixed dosing — not weight-adjusted. The calculator handles reconstitution math for common vial sizes so you inject the right volume every time.

03 — DOSING PROTOCOL

Three tiers, three goals.

beginner10-20 days cycle
Dose
1020 mg
Frequency
Once daily (evening)
Cycle
10-20 days
intermediate20-30 days cycle
Dose
2030 mg
Frequency
Once daily (evening)
Cycle
20-30 days
advanced10-20 days cycle
Dose
100200 mcg
Frequency
Once daily (injection, evening)
Cycle
10-20 days

Injectable dose is much lower than pill dose

04 — SIDE EFFECTS

What people actually report.

  • Drowsiness (that's the point — take at night)
  • Vivid dreams
  • Rare: mild headache
05 — WARNINGS

Before you start.

  • Very safe — it's a tiny natural bioregulator peptide
  • Best used in short cycles — 10-20 days on, then take a break
  • May interact with melatonin supplements — don't double up
06 — STACKING & INTERACTIONS

Combinations worth knowing.

Sleep & Calm Stack

Pinealon fixes your sleep schedule while Selank reduces anxiety. Fall asleep easier and stay asleep longer.

07 — CITATIONS & Q&A

Research behind the claims.

Khavinson V, Diomede F, Mironova E, et al. · Molecules · 2020
Pineal gland-derived peptides from the same Khavinson research program stimulate neurogenesis-related gene expression in neural progenitor cells.

Ask anything, get cited answers.